3-BOC-AMINOMETHYL-AZETIDINE HYDROCHLORID
3-(Boc-Aminomethyl)azetidine-HCl
CAS: 1170108-38-9
Molecular Formula: C9H19ClN2O2
3-BOC-AMINOMETHYL-AZETIDINE HYDROCHLORID - Names and Identifiers
3-BOC-AMINOMETHYL-AZETIDINE HYDROCHLORID - Physico-chemical Properties
| Molecular Formula | C9H19ClN2O2 |
| Molar Mass | 222.71236 |
| Storage Condition | under inert gas (nitrogen or Argon) at 2-8°C |
3-BOC-AMINOMETHYL-AZETIDINE HYDROCHLORID - Risk and Safety
| Hazard Symbols | Xi - Irritant |
3-BOC-AMINOMETHYL-AZETIDINE HYDROCHLORID - Introduction
3-Boc-aminomethylazetidine hydrochloride is an organic compound with the chemical name of 2,4-triazolidin-5-one hydrochloride. Its properties are as follows:
1. appearance: white crystal or crystalline powder.
2. Melting point: about 160-165°C.
3. Solubility: It can be dissolved in water and some organic solvents, such as methanol, ethanol and dimethylformamide.
3-Boc-aminomethylazetidine hydrochloride has a wide range of applications and uses in organic synthesis, commonly used in the following areas:
1. Protecting group: It can be used as an amino protecting agent to form a Boc group by combining with the amino group to protect the reactivity of the amine group to avoid unnecessary side reactions.
2. reaction intermediate: it can be used as an intermediate for the synthesis of other compounds, for example, in the process of preparing polypeptides or drug synthesis, it can be used to protect amine groups and synthesize other amine-related compounds.
The preparation method of 3-Boc-aminomethyl azetidine hydrochloride is as follows:
Reaction of aminomethyl azetidine with tert-butyl chloroformate and heating under basic conditions produces Boc-protected 3-Boc-aminomethyl azetidine. This product is then reacted with hydrochloric acid to form 3-Boc-aminomethylazetidine hydrochloride.
Regarding the safety information of this compound, there is no clear hazard report at present, but the following safety measures should be paid attention to during handling and use:
1. Avoid direct contact with skin and eyes, and wear appropriate personal protective equipment, such as lab gloves and safety glasses.
2. During operation, avoid inhaling the dust or steam of the substance. Be sure to operate in a well-ventilated area.
3. Observe appropriate hazardous material handling and storage regulations during handling and storage.
4. Avoid contact with strong oxidants to avoid dangerous reactions.
In general, scientific laboratories and professionals should follow general laboratory safety practices when using 3-Boc-aminomethylazetidine hydrochloride.
1. appearance: white crystal or crystalline powder.
2. Melting point: about 160-165°C.
3. Solubility: It can be dissolved in water and some organic solvents, such as methanol, ethanol and dimethylformamide.
3-Boc-aminomethylazetidine hydrochloride has a wide range of applications and uses in organic synthesis, commonly used in the following areas:
1. Protecting group: It can be used as an amino protecting agent to form a Boc group by combining with the amino group to protect the reactivity of the amine group to avoid unnecessary side reactions.
2. reaction intermediate: it can be used as an intermediate for the synthesis of other compounds, for example, in the process of preparing polypeptides or drug synthesis, it can be used to protect amine groups and synthesize other amine-related compounds.
The preparation method of 3-Boc-aminomethyl azetidine hydrochloride is as follows:
Reaction of aminomethyl azetidine with tert-butyl chloroformate and heating under basic conditions produces Boc-protected 3-Boc-aminomethyl azetidine. This product is then reacted with hydrochloric acid to form 3-Boc-aminomethylazetidine hydrochloride.
Regarding the safety information of this compound, there is no clear hazard report at present, but the following safety measures should be paid attention to during handling and use:
1. Avoid direct contact with skin and eyes, and wear appropriate personal protective equipment, such as lab gloves and safety glasses.
2. During operation, avoid inhaling the dust or steam of the substance. Be sure to operate in a well-ventilated area.
3. Observe appropriate hazardous material handling and storage regulations during handling and storage.
4. Avoid contact with strong oxidants to avoid dangerous reactions.
In general, scientific laboratories and professionals should follow general laboratory safety practices when using 3-Boc-aminomethylazetidine hydrochloride.
Last Update：2024-04-09 21:54:55
